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Clinical Studies Support Charlotte's Web CBD Clinic™ Topicals as Safe for Massage and Frequent Use - Yahoo Canada Finance

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Studies indicate CBD Clinic™ hemp topicals for massage do not irritate, or penetrate into the bloodstream, after high-frequency, repeated use such as in massage therapy

DENVER, May 25, 2022 /CNW/ - (TSX: CWEB) (OTCQX: CWBHF) Charlotte's Web Holdings, Inc. ("Charlotte's Web," "CW" or the "Company"), the market leader in full-spectrum hemp extract CBD products, today announced results from a series of clinical research studies on frequent use of Charlotte's Web CBD Clinic™ branded topicals in regular and hot stone massage.


Clinical Studies Support Charlotte’s Web CBD Clinic™ Topicals as Safe for Massage and Frequent Use (CNW Group/Charlotte's Web Holdings, Inc.)



Clinical Studies Support Charlotte’s Web CBD Clinic™ Topicals as Safe for Massage and Frequent Use (CNW Group/Charlotte's Web Holdings, Inc.)


The studies included:


  1. Clinical Safety Testing (CBD Clinic™ Relax Massage Cream) – Repeated Insult Patch test


  2. Clinical Safety Testing (CBD Clinic™ Relax Massage Cream) – A five-week 60 subject clinical study

The research found that high-frequency repeated use, typical with massage therapists, of Charlotte's Web CBD Clinic™ massage products did not lead to systemic absorption of cannabinoid metabolites in the bloodstream, nor did the products cause skin irritation.

An expert opinion paper was prepared based on the studies' findings ["Expert Opinion on the Safety Profile of CW Full-Spectrum Hemp Extract in the Practice of Massage Therapy"]. The opinion paper was conducted by third-party clinical research organizations, Charlottes Web's CW Labs division, and a comprehensive literature review. The paper was prepared by Dr. Sherry Bradford, Ph.D. Biochemistry. Dr. Bradford is a former faculty member of University at Buffalo and an editorial board member of The Scientific Federation of Oncology and Cancer (Editor in Chief) and the Journal of Biomolecular Research and Therapy. In the opinion paper, Dr. Bradford found: "The scientific data and research performed on the safety and skin permeation of Charlotte's Web CBD Clinic™ hemp topical products support safe repeated use by MTs [massage therapists], for massage clients, and in normal (heat generated from friction only) and hot stone (additional heat applied) massages."

Story continues

Charlotte's Web, a certified B Corporation, is committed to building a responsible, science-driven and transparent industry for those seeking access to safe, high-quality hemp wellness products. These clinical studies are among many formal scientific investigations supported by the Company's CW Labs division.

"These research findings and expert opinion add to the growing body of evidence-based research for Charlotte's Web CBD Clinic topical products," said Tim Orr, President of Charlotte's Web R&D division, CW Labs. "Massage therapists can be confident they're working with some of the safest, highest-quality hemp CBD products when they choose CBD Clinic by Charlotte's Web."

About CBD Clinic™ Topicals

CBD Clinic™ topicals help target varying levels of discomfort through high-quality, naturally derived active ingredients menthol and camphor. These cooling & heating counterirritants distract the brain's pain signals for the temporary relief of minor aches of muscles and joints. In addition, they are made with moisturizing and essential oils such as clove oil, eucalyptus oil, jojoba oil, and hemp extract (varies by product). Perfect for sore tendons and tissues that need a little extra care.

About CW Labs

Charlotte's Web Labs ("CW Labs") is the research and development division of Charlotte's Web, advancing science around hemp-derived phytocannabinoids, terpenes and flavonoid compounds. CW Labs is comprised of two centers of excellence: The Company's R&D facility located in Louisville, Colorado with expertise in liquid and gas chromatography, mass spectroscopy and organic chemistry, and our formulation chemistry and clinical research R&D center located at the Hauptmann Woodward Research Institute on the campus of the University at Buffalo's Jacobs School of Medicine and The Center for Integrated Global Biomedical Sciences, and is part of the State University of New York (SUNY) network. Research funding and product support are provided by the CW Labs division of Charlotte's Web Inc.

About Charlotte's Web Holdings, Inc.

Charlotte's Web Holdings, Inc., a Certified B Corporation headquartered in Denver, is the market leader in innovative hemp extract wellness products under a family of brands which includes Charlotte's Web™, CBD Medic™, CBD Clinic™, and Harmony Hemp™. Charlotte's Web branded premium quality products start with proprietary hemp genetics that are 100-percent American farm-grown using organic and regenerative cultivation practices. The Company's hemp extracts have naturally occurring botanical compounds including cannabidiol ("CBD"), CBC, CBG, terpenes, flavonoids, and other beneficial compounds. The Company's CW Labs R&D division advances hemp science at two centers of excellence in Louisville, Colorado, and the Hauptmann Woodward Research Institute at the University at Buffalo, part of the State University of New York (SUNY) network. Web product categories include full-spectrum hemp CBD oil tinctures (liquid products), CBD gummies (sleep, stress, exercise recovery), CBD capsules, CBD topical creams and lotions, as well as CBD pet products for dogs. Through its vertically integrated business model, Charlotte's Web maintains stringent control over product quality and consistency with 20+ product lot testing for quality assurance. Charlotte's Web products are distributed to more than 15,000 retail, over 8,000 health care practitioners, and online through the Company's website at www.CharlottesWeb.com. Charlotte's Web's mission is "To unleash the healing powers of botanicals with compassion and science, benefitting the planet and all who live upon it."

Forward-Looking Information

Certain information in this news release constitutes forward-looking statements and forward-looking information within the meaning of applicable securities laws (collectively, ‎‎"forward-looking information"). In some cases, but not necessarily in all cases, forward looking information can be identified by the ‎use of forward-looking terminology such as "plans", "targets", "expects" or "does not expect", "is expected", "an opportunity exists", ‎‎"is positioned", "estimates", "intends", "assumes", "anticipates" or "does not anticipate" or "believes", or variations of such words and ‎phrases or state that certain actions, events or results "may", "could", "would", "might", "will" or "will be taken", "occur" or "be ‎achieved". In addition, any statements that refer to expectations, projections or other characterizations of future events or ‎circumstances contain forward-looking information. ‎Specifically, this news release contains forward-looking information relating to, among others: the future of Charlotte's Web and the impacts of management changes.

Statements containing forward-looking information are not historical facts but instead represent management's current ‎expectations, estimates and projections regarding the future of our business, future plans, strategies, projections, anticipated events ‎and trends, the economy and other future conditions. Forward-looking information is necessarily based on a number of opinions, ‎assumptions and estimates that, while considered reasonable by the Company as of the date of this news release, are subject to ‎known and unknown risks, uncertainties, assumptions and other factors that may cause the actual results, level of activity, ‎performance or achievements to be materially different from those expressed or implied by such forward-looking information. The material factors and assumptions used to develop the forward-looking information herein include, but are not limited to, the following: the impact of the COVID-19 pandemic; the regulatory climate in which the Company currently operates and may in the future operate; consumer interest in CBD; successful sales of the Company's products; and the success of sales and marketing activities. Important factors that could cause actual results and financial condition to differ materially from those indicated in the forward-looking information include, among others, the factors discussed throughout the "Risk Factors" section of the Company's most recently filed Annual Report on Form 10-K for the year ended December 31, 2021 available on www.SEDAR.com and www.sec.gov , and other risk factors contained in other filings with the Securities and Exchange Commission available on www.sec.gov and filings with Canadian securities regulatory authorities available on
www.sedar.com. Except as required by applicable securities laws, the Company undertakes no obligation to publicly update any forward-looking information, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise.


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Charlotte's Web Holdings, Inc. Logo (CNW Group/Charlotte's Web Holdings, Inc.)


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    Blue Nile Wellness Center, we have 4 young girls are working today, young sweet Mia 25 yesterday and young cute Ivy with curve body, fun GFE Lina and sexy Coco are providing deep tissue and sensual massage. Pls call 416-3985777 book appointment and walk in always welcome, back entrance and parking available. 350 Wilson Ave North YorK
  41. Annie Spa:
    🎉🍒ANNIE SPA🎉🍒 ✅7-1001 SANDHURST CIRCLE✅ 👌SCARBOROUGH ON M1V 1Z6👌 ☎️(437) 818-8896☎️ ☎️(416) 291-8879☎️ (FINCH & MCCOWAN) OPEN 10am to 9pm MONDAY to SUNDAY 🔥✅NEW MANAGEMENT💯NEW GIRLS🔥🔥 🔥GORGEOUS NEW YOUNG ASIAN GIRLS - TODAY’s ROSTER INCLUDES: 🔥 Mimi 😍 Feminine with a sexy figure. Judi can provide very good RMT massage and very good service. She'll let you come and go💦 Kiki 😍is beautiful talk sexy student. She has nice bum and very good massage and has great playful service.
  42. ForeverWarden:
    Tuesday at 🫦❤️🔴🟥♾️𝓕𝓞𝓡𝓔𝓥𝓔𝓡 𝓢𝓟𝓐♾️🟥🔴❤️🫦🫦2190 Warden Ave, Unit 201, Scarborough 𝟰𝟭𝟲-𝟴𝟬𝟬-𝟳𝟴𝟴𝟳: Cindy, Tracy & Vivian. Cindy is a slim beauty, 5’4”, natural C Cups & wonderfully long nipples. Her massage is nice, her bbbj will drive you wild & her cfs finish is a dream come true. Tracy is an incredibly cute & pretty Japanese/Taiwanese mixed spinner, about 5’1” and 100 lbs. She is very popular
  43. Endless Joy Spa:
    ✨✨✨✨✨[GRAND OPENING]✨✨✨✨✨ 💞Endless Joy Spa💞 🎇 (155 East Beaver Creek Rd Unit #8, Richmond Hill) 416-731-8565🎇10am-2am, Slim Sexy Chinese Kiki, Slim Petite Chinese Suki, Tall Slim Sexy Chinese Kelly, Young Sexy Chinese Abie.
  44. Lulu1980:
    Phoenix blossom Spa ♨️♨️♨️every day 3 girls 💐🌹💐🌹🌹Jessica and Cici and Jenny 😘😘😘sexy body Jessica very good body slide🔥🔥🔥🔥Jenny very good table shower body scrub 👍👍👍👍Cici deep tissue massage 💪💪💪💪💪5124 Dundas W Etobicoke ☎️416-817 3366
  45. Red Rose Spa:
    🌸 We have 5 hot brown girls today 🌸 ASHA, PAYAL PEARL, MONIKA, KIRAN, AMANDA, MALAY, NISHA, SANA, ANGEL 🌸 2588 Birchmount 🌸 2 Invergordon 🌸 647-702-8800 🌸 Please visit for a great erotic massage
  46. Lily Spa:
    ❤️ SANA, CAMILLA and KK are here today for your massage needs ❤️ Lily Spa ❤️ 2190 McNicoll ❤️ Scarborough ❤️ M1V 5M2 ❤️ (647) 531-8288 ❤️
  47. bumika.vashi:
    (((आपको बिना नाटक या नखरे करने वाला सर्विस चाहे तोह याद करना. ))) If you want Service without Drama or Tantrums, Remember it. Will Try To Give You The Best Possible Sweating Experience With Full Company. TAKE MY WORD.?? Don't Waste Your Time And Money In Some Other Place Where You are Really Upset Loosing Out Both Money And Fun. Ok Try With Our Girls Once Then Your Visit Will Be Regular To Me.... _________________N O T E_________________ If u like my services Please Please Do not forget to
  48. Sparkling Spa:
    SPARKLING SPA 50 LOCKRIDGE AVE UNIT 8!! INTERNATIONAL GIRLS FOR A VARIETY OF APPETITES!! KOREAN NYMPHO SUMMER & SHANGHAI SENSATION JENNIFER!!!☎️(905) 604-8186 Spa Land Line☎️ ☎️(437) 446-6688 NEW Spa Cell Phone 50 LOCKRIDGE AVE UNIT#8 NO SPA LIKE US ANYWHERE NEAR US
  49. Lily Spa:
    ❤️ KAJAL, CAMILLA and KK are here today for your massage needs ❤️ Lily Spa ❤️ 2190 McNicoll ❤️ Scarborough ❤️ M1V 5M2 ❤️ (647) 531-8288 ❤️
  50. Shanelobe:
    Bbfa
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